BDBM50175442 5-(2-chlorophenyl)furan-2-carboxylic acid::CHEMBL200238::cid_784625

SMILES: OC(=O)c1ccc(o1)-c1ccccc1Cl

InChI Key: InChIKey=PJGGWIHXGHQXMM-UHFFFAOYSA-N

Data: 11 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50175442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CR5RRG
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Fe(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	511	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Mn(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Ni(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Co(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 10 uM Nickel				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 100 uM Manganese				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 5 uM Manganese				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 6 uM Iron				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 1 uM Cobalt				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175442 (5-(2-chlorophenyl)furan-2-carboxylic acid | CHEMBL...) Show SMILES OC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 100 uM Cobalt				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)