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BDBM50175544 CHEMBL198664::N-Hydroxy-4-oxo-4-(4-trifluoromethyl-phenyl)-butyramide

SMILES: ONC(=O)CCC(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=PUMIZAOKQSLDEL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175544   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interstitial collagenase


(Homo sapiens (Human))
BDBM50175544
PNG
(CHEMBL198664 | N-Hydroxy-4-oxo-4-(4-trifluoromethy...)
Show SMILES ONC(=O)CCC(=O)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C11H10F3NO3/c12-11(13,14)8-3-1-7(2-4-8)9(16)5-6-10(17)15-18/h1-4,18H,5-6H2,(H,15,17)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
3n/an/an/an/an/an/an/an/a



De Novo Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards (MMP-1) matrix metalloproteinase-1


J Med Chem 48: 6585-96 (2005)


Article DOI: 10.1021/jm050196j
BindingDB Entry DOI: 10.7270/Q20K284B
More data for this
Ligand-Target Pair