null
SMILES: COC(=O)C1C2CCC(CC1c1ccc(cc1)-c1cncc(OC)c1)N2
InChI Key: InChIKey=HFDAIKHXHSHODJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50175642 (CHEMBL199743 | methyl 3-(4-(5-methoxypyridin-3-yl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortex | Bioorg Med Chem Lett 16: 217-20 (2005) Article DOI: 10.1016/j.bmcl.2005.09.016 BindingDB Entry DOI: 10.7270/Q2R210Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50175642 (CHEMBL199743 | methyl 3-(4-(5-methoxypyridin-3-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 332 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortex | Bioorg Med Chem Lett 16: 217-20 (2005) Article DOI: 10.1016/j.bmcl.2005.09.016 BindingDB Entry DOI: 10.7270/Q2R210Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50175642 (CHEMBL199743 | methyl 3-(4-(5-methoxypyridin-3-yl)...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 739 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NET in rat caudate-putamen | Bioorg Med Chem Lett 16: 217-20 (2005) Article DOI: 10.1016/j.bmcl.2005.09.016 BindingDB Entry DOI: 10.7270/Q2R210Z2 | |||||||||||
More data for this Ligand-Target Pair |