BDBM50175678 CHEMBL3809883

SMILES: Cl.COc1ccc(CCN2CCC(CCc3ccccc3)CC2)cc1

InChI Key: InChIKey=NYCRIDUOAMNNCI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50175678 (CHEMBL3809883) Show SMILES Cl.COc1ccc(CCN2CCC(CCc3ccccc3)CC2)cc1 Show InChI InChI=1S/C22H29NO.ClH/c1-24-22-11-9-20(10-12-22)13-16-23-17-14-21(15-18-23)8-7-19-5-3-2-4-6-19;/h2-6,9-12,21H,7-8,13-18H2,1H3;1H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striata vesicles homogenate after 8 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 2997-3000 (2016) BindingDB Entry DOI: 10.7270/Q2MC91ZC
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50175678 (CHEMBL3809883) Show SMILES Cl.COc1ccc(CCN2CCC(CCc3ccccc3)CC2)cc1 Show InChI InChI=1S/C22H29NO.ClH/c1-24-22-11-9-20(10-12-22)13-16-23-17-14-21(15-18-23)8-7-19-5-3-2-4-6-19;/h2-6,9-12,21H,7-8,13-18H2,1H3;1H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Displacement of [3H]DTBZ from VMAT2 in rat whole brain vesicles homogenate after 30 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 2997-3000 (2016) BindingDB Entry DOI: 10.7270/Q2MC91ZC
					More data for this Ligand-Target Pair