BDBM50175718 (4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1-yl)(4-methylpiperazin-1-yl)methanone::CHEMBL426470

SMILES: CN1CCN(CC1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1

InChI Key: InChIKey=AMHXVALGTLRIMQ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175718 ((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...) Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H33N5O/c1-29-18-20-31(21-19-29)26(33)30-15-12-27(13-16-30,24-10-6-3-7-11-24)25-28-14-17-32(25)22-23-8-4-2-5-9-23/h2-11,14,17H,12-13,15-16,18-22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	161	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175718 ((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...) Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H33N5O/c1-29-18-20-31(21-19-29)26(33)30-15-12-27(13-16-30,24-10-6-3-7-11-24)25-28-14-17-32(25)22-23-8-4-2-5-9-23/h2-11,14,17H,12-13,15-16,18-22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	858	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175718 ((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...) Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H33N5O/c1-29-18-20-31(21-19-29)26(33)30-15-12-27(13-16-30,24-10-6-3-7-11-24)25-28-14-17-32(25)22-23-8-4-2-5-9-23/h2-11,14,17H,12-13,15-16,18-22H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair