BDBM50175724 4-(1-(3-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-carboxamide::CHEMBL381674

SMILES: Fc1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)c1

InChI Key: InChIKey=VAVXEYAGRWBBSX-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175724 (4-(1-(3-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...) Show SMILES Fc1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C28H27FN4O/c29-24-11-7-8-22(20-24)21-33-19-16-30-26(33)28(23-9-3-1-4-10-23)14-17-32(18-15-28)27(34)31-25-12-5-2-6-13-25/h1-13,16,19-20H,14-15,17-18,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175724 (4-(1-(3-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...) Show SMILES Fc1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C28H27FN4O/c29-24-11-7-8-22(20-24)21-33-19-16-30-26(33)28(23-9-3-1-4-10-23)14-17-32(18-15-28)27(34)31-25-12-5-2-6-13-25/h1-13,16,19-20H,14-15,17-18,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175724 (4-(1-(3-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...) Show SMILES Fc1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C28H27FN4O/c29-24-11-7-8-22(20-24)21-33-19-16-30-26(33)28(23-9-3-1-4-10-23)14-17-32(18-15-28)27(34)31-25-12-5-2-6-13-25/h1-13,16,19-20H,14-15,17-18,21H2,(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair