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BDBM50175732 4-(1-(4-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-carboxamide::CHEMBL199684

SMILES: Fc1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)cc1

InChI Key: InChIKey=BWAOWNSFWHQHCH-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175732   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (human))
BDBM50175732
PNG
(4-(1-(4-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Show SMILES Fc1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C28H27FN4O/c29-24-13-11-22(12-14-24)21-33-20-17-30-26(33)28(23-7-3-1-4-8-23)15-18-32(19-16-28)27(34)31-25-9-5-2-6-10-25/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
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PC cid
PC sid
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Similars

Article
PubMed
203n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)

More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (human))
BDBM50175732
PNG
(4-(1-(4-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Show SMILES Fc1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C28H27FN4O/c29-24-13-11-22(12-14-24)21-33-20-17-30-26(33)28(23-7-3-1-4-8-23)15-18-32(19-16-28)27(34)31-25-9-5-2-6-10-25/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
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Article
PubMed
2.16E+3n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)

More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (human))
BDBM50175732
PNG
(4-(1-(4-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Show SMILES Fc1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C28H27FN4O/c29-24-13-11-22(12-14-24)21-33-20-17-30-26(33)28(23-7-3-1-4-8-23)15-18-32(19-16-28)27(34)31-25-9-5-2-6-10-25/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
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Article
PubMed
>4.65E+3n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)

More data for this
Ligand-Target Pair