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BDBM50175733 4-(1-benzyl-1H-imidazol-2-yl)-N-(2-fluorophenyl)-4-phenylpiperidine-1-carboxamide::CHEMBL371266

SMILES: Fc1ccccc1NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1

InChI Key: InChIKey=LFXQMSUBNHNYDM-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175733   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (human))
BDBM50175733
PNG
(4-(1-benzyl-1H-imidazol-2-yl)-N-(2-fluorophenyl)-4...)
Show SMILES Fc1ccccc1NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H27FN4O/c29-24-13-7-8-14-25(24)31-27(34)32-18-15-28(16-19-32,23-11-5-2-6-12-23)26-30-17-20-33(26)21-22-9-3-1-4-10-22/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
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PC cid
PC sid
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Similars

Article
PubMed
29n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)

More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (human))
BDBM50175733
PNG
(4-(1-benzyl-1H-imidazol-2-yl)-N-(2-fluorophenyl)-4...)
Show SMILES Fc1ccccc1NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H27FN4O/c29-24-13-7-8-14-25(24)31-27(34)32-18-15-28(16-19-32,23-11-5-2-6-12-23)26-30-17-20-33(26)21-22-9-3-1-4-10-22/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
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PC sid
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Article
PubMed
318n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)

More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (human))
BDBM50175733
PNG
(4-(1-benzyl-1H-imidazol-2-yl)-N-(2-fluorophenyl)-4...)
Show SMILES Fc1ccccc1NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H27FN4O/c29-24-13-7-8-14-25(24)31-27(34)32-18-15-28(16-19-32,23-11-5-2-6-12-23)26-30-17-20-33(26)21-22-9-3-1-4-10-22/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
PDB

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UniChem

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Article
PubMed
2.52E+3n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)

More data for this
Ligand-Target Pair