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BDBM50175735 4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-carboxamide::CHEMBL199871

SMILES: Fc1ccccc1Cn1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1

InChI Key: InChIKey=CJDRHQVGEOEZPW-UHFFFAOYSA-N

Data: 3 KI

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175735   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50175735
PNG
(4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Show SMILES Fc1ccccc1Cn1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H27FN4O/c29-25-14-8-7-9-22(25)21-33-20-17-30-26(33)28(23-10-3-1-4-11-23)15-18-32(19-16-28)27(34)31-24-12-5-2-6-13-24/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
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PC cid
PC sid
UniChem
Article
PubMed
72n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.025
BindingDB Entry DOI: 10.7270/Q2ZK5G70
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50175735
PNG
(4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Show SMILES Fc1ccccc1Cn1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H27FN4O/c29-25-14-8-7-9-22(25)21-33-20-17-30-26(33)28(23-10-3-1-4-11-23)15-18-32(19-16-28)27(34)31-24-12-5-2-6-13-24/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
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PC sid
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Article
PubMed
116n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.025
BindingDB Entry DOI: 10.7270/Q2ZK5G70
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50175735
PNG
(4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Show SMILES Fc1ccccc1Cn1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H27FN4O/c29-25-14-8-7-9-22(25)21-33-20-17-30-26(33)28(23-10-3-1-4-11-23)15-18-32(19-16-28)27(34)31-24-12-5-2-6-13-24/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)
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PC cid
PC sid
UniChem
Article
PubMed
428n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.025
BindingDB Entry DOI: 10.7270/Q2ZK5G70
More data for this
Ligand-Target Pair