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BDBM50175764 1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-(3-(diethylamino)propoxy)phenyl)-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)urea dihydrochloride::CHEMBL538571

SMILES: CCCCn1c2ncccc2c(-c2cccc(OCCCN(CC)CC)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O

InChI Key: InChIKey=NCTLCYGTFVEYGL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175764   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)		BDBM50175764
PNG
(1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...)
Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCN(CC)CC)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O
Show InChI InChI=1S/C38H52N6O3/c1-8-11-20-44-36-30(17-13-18-40-36)33(27-15-12-16-29(22-27)47-21-14-19-43(9-2)10-3)35(37(44)45)42-38(46)41-34-31(25(4)5)23-28(39)24-32(34)26(6)7/h12-13,15-18,22-26H,8-11,14,19-21,39H2,1-7H3,(H2,41,42,46)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 452n/an/an/an/an/an/a



Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against ACAT in rat macrophages

Bioorg Med Chem Lett 16: 44-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.056
BindingDB Entry DOI: 10.7270/Q2PG1SH8
More data for this
Ligand-Target Pair