BDBM50175770 1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-(2-hydroxyethoxy)phenyl)-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)urea hydrochloride::CHEMBL538826

SMILES: CCCCn1c2ncccc2c(-c2cccc(OCCO)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O

InChI Key: InChIKey=FWSUTTPJCUDJOG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50175770 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCO)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C33H41N5O4/c1-6-7-14-38-31-25(12-9-13-35-31)28(22-10-8-11-24(17-22)42-16-15-39)30(32(38)40)37-33(41)36-29-26(20(2)3)18-23(34)19-27(29)21(4)5/h8-13,17-21,39H,6-7,14-16,34H2,1-5H3,(H2,36,37,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair