BDBM50175778 1-methyl-5-(2-phenylH-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine::CHEMBL370379

SMILES: Cn1nc(N)c2cc(nnc12)-c1c(nn2ccccc12)-c1ccccc1

InChI Key: InChIKey=XENVXRJYANOSAS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50175778 (1-methyl-5-(2-phenylH-pyrazolo[1,5-a]pyridin-3-yl)...) Show SMILES Cn1nc(N)c2cc(nnc12)-c1c(nn2ccccc12)-c1ccccc1 Show InChI InChI=1S/C19H15N7/c1-25-19-13(18(20)24-25)11-14(21-22-19)16-15-9-5-6-10-26(15)23-17(16)12-7-3-2-4-8-12/h2-11H,1H3,(H2,20,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human ERK2				Bioorg Med Chem Lett 16: 55-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.055 BindingDB Entry DOI: 10.7270/Q2Q23ZSV
					More data for this Ligand-Target Pair