BDBM50175851 3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-phenylpropanamide::CHEMBL383825
SMILES: O=C(CCN1CCC(Cc2cnc[nH]2)CC1)Nc1ccccc1
InChI Key: InChIKey=VYKYONMUUZZHKY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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HRH3 (GUINEA PIG) | BDBM50175851 (3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-p...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Schering Plough Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in guinea pig brain | Bioorg Med Chem Lett 16: 395-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.076 BindingDB Entry DOI: 10.7270/Q29S1QK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HRH3 (GUINEA PIG) | BDBM50175851 (3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-p...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.26 | n/a | n/a | n/a | n/a | n/a |
The Schering Plough Research Institute Curated by ChEMBL | Assay Description Antagonist potency against histamine H3 receptor in an electrically stimulated guinea pig ileum | Bioorg Med Chem Lett 16: 395-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.076 BindingDB Entry DOI: 10.7270/Q29S1QK1 | |||||||||||
More data for this Ligand-Target Pair |