null

SMILES: COc1ccc(cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ccc12)C#CC(C)(C)N

InChI Key: InChIKey=XNDSNFANNLNJCB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Mus musculus (mouse))	BDBM50176007 (3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...) Show SMILES COc1ccc(cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ccc12)C#CC(C)(C)N Show InChI InChI=1S/C24H21F2N5O/c1-24(2,27)11-10-14-4-8-20(32-3)17(12-14)22-16-6-9-21(29-23(16)31-30-22)28-19-7-5-15(25)13-18(19)26/h4-9,12-13H,27H2,1-3H3,(H2,28,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibitory activity against murine p38alpha MAPK				Bioorg Med Chem Lett 16: 262-6 (2005) Article DOI: 10.1016/j.bmcl.2005.10.015 BindingDB Entry DOI: 10.7270/Q2DJ5F6T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50176007 (3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...) Show SMILES COc1ccc(cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ccc12)C#CC(C)(C)N Show InChI InChI=1S/C24H21F2N5O/c1-24(2,27)11-10-14-4-8-20(32-3)17(12-14)22-16-6-9-21(29-23(16)31-30-22)28-19-7-5-15(25)13-18(19)26/h4-9,12-13H,27H2,1-3H3,(H2,28,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibitory activity against JNK2				Bioorg Med Chem Lett 16: 262-6 (2005) Article DOI: 10.1016/j.bmcl.2005.10.015 BindingDB Entry DOI: 10.7270/Q2DJ5F6T
					More data for this Ligand-Target Pair