BindingDB logo
myBDB logout

null

SMILES: COc1ccc(CCC(C)(C)O)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12

InChI Key: InChIKey=MYNAYBBCIXLNLB-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176009   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Mus musculus (mouse))		BDBM50176009
PNG
(4-(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-...)
Show SMILES COc1ccc(CCC(C)(C)O)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12
Show InChI InChI=1S/C23H23F2N5O2/c1-23(2,31)9-8-13-4-7-19(32-3)15(10-13)20-16-12-26-22(28-21(16)30-29-20)27-18-6-5-14(24)11-17(18)25/h4-7,10-12,31H,8-9H2,1-3H3,(H2,26,27,28,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibitory activity against murine p38alpha MAPK

Bioorg Med Chem Lett 16: 262-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.015
BindingDB Entry DOI: 10.7270/Q2DJ5F6T
More data for this
Ligand-Target Pair