BDBM50176413 2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-propyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::CHEMBL203925

SMILES: CCCn1cnc2c(-c3ccc(Cl)cc3)n(nc2c1=O)-c1ccccc1Cl

InChI Key: InChIKey=ZAXLGOKJJSFMKC-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50176413 (2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-propyl-2H-...) Show SMILES CCCn1cnc2c(-c3ccc(Cl)cc3)n(nc2c1=O)-c1ccccc1Cl Show InChI InChI=1S/C20H16Cl2N4O/c1-2-11-25-12-23-17-18(20(25)27)24-26(16-6-4-3-5-15(16)22)19(17)13-7-9-14(21)10-8-13/h3-10,12H,2,11H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cells				Bioorg Med Chem Lett 16: 731-6 (2005) Article DOI: 10.1016/j.bmcl.2005.10.019 BindingDB Entry DOI: 10.7270/Q2TM79PM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50176413 (2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-propyl-2H-...) Show SMILES CCCn1cnc2c(-c3ccc(Cl)cc3)n(nc2c1=O)-c1ccccc1Cl Show InChI InChI=1S/C20H16Cl2N4O/c1-2-11-25-12-23-17-18(20(25)27)24-26(16-6-4-3-5-15(16)22)19(17)13-7-9-14(21)10-8-13/h3-10,12H,2,11H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assay				Bioorg Med Chem Lett 16: 731-6 (2005) Article DOI: 10.1016/j.bmcl.2005.10.019 BindingDB Entry DOI: 10.7270/Q2TM79PM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50176413 (2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-propyl-2H-...) Show SMILES CCCn1cnc2c(-c3ccc(Cl)cc3)n(nc2c1=O)-c1ccccc1Cl Show InChI InChI=1S/C20H16Cl2N4O/c1-2-11-25-12-23-17-18(20(25)27)24-26(16-6-4-3-5-15(16)22)19(17)13-7-9-14(21)10-8-13/h3-10,12H,2,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Binding affinity to human CB2 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 16: 731-6 (2005) Article DOI: 10.1016/j.bmcl.2005.10.019 BindingDB Entry DOI: 10.7270/Q2TM79PM
					More data for this Ligand-Target Pair