BDBM50176431 CHEMBL371252::N-(3-acetyl-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-1-(2-methoxyethyl)-2-oxo-1,2-dihydro-1,8-naphthyridin-4-yl)acetamide

SMILES: COCCn1c2nc(-c3ccc(Cl)cc3Cl)c(cc2c(NC(C)=O)c(C(C)=O)c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=FBTJXTNIWICRLD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50176431 (CHEMBL371252 | N-(3-acetyl-6-(4-chlorophenyl)-7-(2...) Show SMILES COCCn1c2nc(-c3ccc(Cl)cc3Cl)c(cc2c(NC(C)=O)c(C(C)=O)c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H22Cl3N3O4/c1-14(34)23-25(31-15(2)35)21-13-20(16-4-6-17(28)7-5-16)24(19-9-8-18(29)12-22(19)30)32-26(21)33(27(23)36)10-11-37-3/h4-9,12-13H,10-11H2,1-3H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at the CB2 receptor				Bioorg Med Chem Lett 16: 681-5 (2005) Article DOI: 10.1016/j.bmcl.2005.10.028 BindingDB Entry DOI: 10.7270/Q2PZ58CM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50176431 (CHEMBL371252 | N-(3-acetyl-6-(4-chlorophenyl)-7-(2...) Show SMILES COCCn1c2nc(-c3ccc(Cl)cc3Cl)c(cc2c(NC(C)=O)c(C(C)=O)c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H22Cl3N3O4/c1-14(34)23-25(31-15(2)35)21-13-20(16-4-6-17(28)7-5-16)24(19-9-8-18(29)12-22(19)30)32-26(21)33(27(23)36)10-11-37-3/h4-9,12-13H,10-11H2,1-3H3,(H,31,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at the CB1 receptor				Bioorg Med Chem Lett 16: 681-5 (2005) Article DOI: 10.1016/j.bmcl.2005.10.028 BindingDB Entry DOI: 10.7270/Q2PZ58CM
					More data for this Ligand-Target Pair