BDBM50176437 CHEMBL381677::N-(6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-3-isopropyl-1-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-4-yl)acetamide

SMILES: CC(C)c1c(NC(C)=O)c2cc(-c3ccc(Cl)cc3)c(nc2n(C)c1=O)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=RNMRJQUHDLMTCB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50176437 (CHEMBL381677 | N-(6-(4-chlorophenyl)-7-(2,4-dichlo...) Show SMILES CC(C)c1c(NC(C)=O)c2cc(-c3ccc(Cl)cc3)c(nc2n(C)c1=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl3N3O2/c1-13(2)22-24(30-14(3)33)20-12-19(15-5-7-16(27)8-6-15)23(31-25(20)32(4)26(22)34)18-10-9-17(28)11-21(18)29/h5-13H,1-4H3,(H,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at the CB1 receptor				Bioorg Med Chem Lett 16: 681-5 (2005) Article DOI: 10.1016/j.bmcl.2005.10.028 BindingDB Entry DOI: 10.7270/Q2PZ58CM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50176437 (CHEMBL381677 | N-(6-(4-chlorophenyl)-7-(2,4-dichlo...) Show SMILES CC(C)c1c(NC(C)=O)c2cc(-c3ccc(Cl)cc3)c(nc2n(C)c1=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl3N3O2/c1-13(2)22-24(30-14(3)33)20-12-19(15-5-7-16(27)8-6-15)23(31-25(20)32(4)26(22)34)18-10-9-17(28)11-21(18)29/h5-13H,1-4H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at the CB2 receptor				Bioorg Med Chem Lett 16: 681-5 (2005) Article DOI: 10.1016/j.bmcl.2005.10.028 BindingDB Entry DOI: 10.7270/Q2PZ58CM
					More data for this Ligand-Target Pair