BDBM50176474 (5,8-dichloro-1-methyl-3,4-dihydro-1H-benzo[4,5]furo[2,3-c]pyran-1-yl)-acetic acid::CHEMBL383598

SMILES: CC1(CC(O)=O)OCCc2c1oc1c(Cl)ccc(Cl)c21

InChI Key: InChIKey=QRJGLGSVEKFLBA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50176474 ((5,8-dichloro-1-methyl-3,4-dihydro-1H-benzo[4,5]fu...) Show SMILES CC1(CC(O)=O)OCCc2c1oc1c(Cl)ccc(Cl)c21 Show InChI InChI=1S/C14H12Cl2O4/c1-14(6-10(17)18)13-7(4-5-19-14)11-8(15)2-3-9(16)12(11)20-13/h2-3H,4-6H2,1H3,(H,17,18)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [alpha-32P]GTP from recombinant HCV NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 16: 457-60 (2005) Article DOI: 10.1016/j.bmcl.2005.08.114 BindingDB Entry DOI: 10.7270/Q25X28H8
					More data for this Ligand-Target Pair