BDBM50176488 ((R)-5-cyano-8-methyl-1-propyl-3,4-dihydro-1H-benzo[4,5]thieno[2,3-c]pyran-1-yl)-acetic acid::CHEMBL199954

SMILES: CCC[C@]1(CC(O)=O)OCCc2c1sc1c(C)ccc(C#N)c21

InChI Key: InChIKey=YNXRVNCHLCERRJ-GOSISDBHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50176488 (((R)-5-cyano-8-methyl-1-propyl-3,4-dihydro-1H-benz...) Show SMILES CCC[C@]1(CC(O)=O)OCCc2c1sc1c(C)ccc(C#N)c21 Show InChI InChI=1S/C18H19NO3S/c1-3-7-18(9-14(20)21)17-13(6-8-22-18)15-12(10-19)5-4-11(2)16(15)23-17/h4-5H,3,6-9H2,1-2H3,(H,20,21)/t18-/m1/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [alpha-32P]GTP from recombinant HCV NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 16: 457-60 (2005) Article DOI: 10.1016/j.bmcl.2005.08.114 BindingDB Entry DOI: 10.7270/Q25X28H8
					More data for this Ligand-Target Pair