BDBM50176606 2-(3-((3-fluoro-4-(trifluoromethyl)benzyl)carbamoyl)-4-methoxybenzyl)butanoic acid::CHEMBL201803

SMILES: CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(c(F)c1)C(F)(F)F)C(O)=O

InChI Key: InChIKey=JLGDOBIVWHHFDE-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50176606 (2-(3-((3-fluoro-4-(trifluoromethyl)benzyl)carbamoy...) Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(c(F)c1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-14(20(28)29)8-12-5-7-18(30-2)15(9-12)19(27)26-11-13-4-6-16(17(22)10-13)21(23,24)25/h4-7,9-10,14H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARgamma transfected in HEK293 cells				Bioorg Med Chem Lett 16: 554-8 (2005) Article DOI: 10.1016/j.bmcl.2005.10.049 BindingDB Entry DOI: 10.7270/Q2DF6QS3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50176606 (2-(3-((3-fluoro-4-(trifluoromethyl)benzyl)carbamoy...) Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(c(F)c1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-14(20(28)29)8-12-5-7-18(30-2)15(9-12)19(27)26-11-13-4-6-16(17(22)10-13)21(23,24)25/h4-7,9-10,14H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARdelta transfected in HEK293 cells				Bioorg Med Chem Lett 16: 554-8 (2005) Article DOI: 10.1016/j.bmcl.2005.10.049 BindingDB Entry DOI: 10.7270/Q2DF6QS3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50176606 (2-(3-((3-fluoro-4-(trifluoromethyl)benzyl)carbamoy...) Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(c(F)c1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-14(20(28)29)8-12-5-7-18(30-2)15(9-12)19(27)26-11-13-4-6-16(17(22)10-13)21(23,24)25/h4-7,9-10,14H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARalpha transfected in HEK293 cells				Bioorg Med Chem Lett 16: 554-8 (2005) Article DOI: 10.1016/j.bmcl.2005.10.049 BindingDB Entry DOI: 10.7270/Q2DF6QS3
					More data for this Ligand-Target Pair