null

SMILES: COC1(CN2CCC1CC2)C#CC(O)(C1CCC1)c1ccccn1

InChI Key: InChIKey=URXQXNPRSDVQNH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50176707 (1-cyclobutyl-3-(3-methoxyquinuclidin-3-yl)-1-(pyri...) Show SMILES COC1(CN2CCC1CC2)C#CC(O)(C1CCC1)c1ccccn1 |THB:1:2:5.6:9.8,(8.86,-3.54,;10.4,-3.54,;11.18,-4.88,;11.71,-6.17,;13.03,-5.15,;14.51,-5.42,;13.89,-4.14,;12.44,-3.89,;12.1,-2.29,;12.8,-3.25,;9.82,-5.64,;8.47,-6.4,;7.13,-7.15,;6.37,-5.81,;7.88,-8.5,;7.46,-9.97,;8.94,-10.39,;9.36,-8.91,;5.78,-7.91,;5.76,-9.45,;4.42,-10.21,;3.09,-9.42,;3.11,-7.87,;4.45,-7.12,)| Show InChI InChI=1S/C20H26N2O2/c1-24-19(15-22-13-8-16(19)9-14-22)10-11-20(23,17-5-4-6-17)18-7-2-3-12-21-18/h2-3,7,12,16-17,23H,4-6,8-9,13-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M3 receptor				Bioorg Med Chem Lett 16: 373-7 (2005) Article DOI: 10.1016/j.bmcl.2005.09.079 BindingDB Entry DOI: 10.7270/Q2T72J70
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50176707 (1-cyclobutyl-3-(3-methoxyquinuclidin-3-yl)-1-(pyri...) Show SMILES COC1(CN2CCC1CC2)C#CC(O)(C1CCC1)c1ccccn1 |THB:1:2:5.6:9.8,(8.86,-3.54,;10.4,-3.54,;11.18,-4.88,;11.71,-6.17,;13.03,-5.15,;14.51,-5.42,;13.89,-4.14,;12.44,-3.89,;12.1,-2.29,;12.8,-3.25,;9.82,-5.64,;8.47,-6.4,;7.13,-7.15,;6.37,-5.81,;7.88,-8.5,;7.46,-9.97,;8.94,-10.39,;9.36,-8.91,;5.78,-7.91,;5.76,-9.45,;4.42,-10.21,;3.09,-9.42,;3.11,-7.87,;4.45,-7.12,)| Show InChI InChI=1S/C20H26N2O2/c1-24-19(15-22-13-8-16(19)9-14-22)10-11-20(23,17-5-4-6-17)18-7-2-3-12-21-18/h2-3,7,12,16-17,23H,4-6,8-9,13-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M2 receptor				Bioorg Med Chem Lett 16: 373-7 (2005) Article DOI: 10.1016/j.bmcl.2005.09.079 BindingDB Entry DOI: 10.7270/Q2T72J70
					More data for this Ligand-Target Pair