BDBM50176976 8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide::CHEMBL225622

SMILES: Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC2CCCCC2)c2CCCc3cc(Cl)ccc3-c12

InChI Key: InChIKey=ADAVAHIZKNKQSU-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50176976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Mus musculus (Mouse))	BDBM50176976 (8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4...) Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC2CCCCC2)c2CCCc3cc(Cl)ccc3-c12 Show InChI InChI=1S/C25H24Cl3N3O/c26-16-9-11-19-15(13-16)5-4-8-20-23(25(32)29-18-6-2-1-3-7-18)30-31(24(19)20)22-12-10-17(27)14-21(22)28/h9-14,18H,1-8H2,(H,29,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Sassari Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain				J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50176976 (8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4...) Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC2CCCCC2)c2CCCc3cc(Cl)ccc3-c12 Show InChI InChI=1S/C25H24Cl3N3O/c26-16-9-11-19-15(13-16)5-4-8-20-23(25(32)29-18-6-2-1-3-7-18)30-31(24(19)20)22-12-10-17(27)14-21(22)28/h9-14,18H,1-8H2,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Sassari Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleen				J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Mus musculus (Mouse))	BDBM50176976 (8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4...) Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC2CCCCC2)c2CCCc3cc(Cl)ccc3-c12 Show InChI InChI=1S/C25H24Cl3N3O/c26-16-9-11-19-15(13-16)5-4-8-20-23(25(32)29-18-6-2-1-3-7-18)30-31(24(19)20)22-12-10-17(27)14-21(22)28/h9-14,18H,1-8H2,(H,29,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL					Assay Description Displacement of [3H]-CP55,940 from CB1 receptor in mouse whole brain membranes after 60 mins by liquid scintillation spectrometry				Eur J Med Chem 121: 194-208 (2016) Article DOI: 10.1016/j.ejmech.2016.05.011 BindingDB Entry DOI: 10.7270/Q2PR7XXB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50176976 (8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4...) Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC2CCCCC2)c2CCCc3cc(Cl)ccc3-c12 Show InChI InChI=1S/C25H24Cl3N3O/c26-16-9-11-19-15(13-16)5-4-8-20-23(25(32)29-18-6-2-1-3-7-18)30-31(24(19)20)22-12-10-17(27)14-21(22)28/h9-14,18H,1-8H2,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL					Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor transfected in CHO cell membranes after 60 mins by liquid scintillation spectrometry				Eur J Med Chem 121: 194-208 (2016) Article DOI: 10.1016/j.ejmech.2016.05.011 BindingDB Entry DOI: 10.7270/Q2PR7XXB
					More data for this Ligand-Target Pair