BDBM50176996 CHEMBL3813969

SMILES: O=C(Nc1ccc(Cn2cncn2)cc1)c1ccccc1NCc1ccncc1

InChI Key: InChIKey=LDIFNPCLKQRUAU-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50176996 (CHEMBL3813969) Show SMILES O=C(Nc1ccc(Cn2cncn2)cc1)c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H20N6O/c29-22(27-19-7-5-18(6-8-19)14-28-16-24-15-26-28)20-3-1-2-4-21(20)25-13-17-9-11-23-12-10-17/h1-12,15-16,25H,13-14H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Swiss Federal Institute of Technology (ETH) Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin)				J Med Chem 59: 4077-86 (2016) BindingDB Entry DOI: 10.7270/Q2FN184P
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50176996 (CHEMBL3813969) Show SMILES O=C(Nc1ccc(Cn2cncn2)cc1)c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H20N6O/c29-22(27-19-7-5-18(6-8-19)14-28-16-24-15-26-28)20-3-1-2-4-21(20)25-13-17-9-11-23-12-10-17/h1-12,15-16,25H,13-14H2,(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Swiss Federal Institute of Technology (ETH) Curated by ChEMBL					Assay Description Inhibition of VEGFR1 (unknown origin)				J Med Chem 59: 4077-86 (2016) BindingDB Entry DOI: 10.7270/Q2FN184P
					More data for this Ligand-Target Pair