BDBM50177020 CHEMBL3815113

SMILES: FC(F)(F)c1ccc(CN2CCN(CC2c2ccccc2)c2ccccc2)cn1

InChI Key: InChIKey=MGAXXAQFWJEKCP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50177020 (CHEMBL3815113) Show SMILES FC(F)(F)c1ccc(CN2CCN(CC2c2ccccc2)c2ccccc2)cn1 Show InChI InChI=1S/C23H22F3N3/c24-23(25,26)22-12-11-18(15-27-22)16-29-14-13-28(20-9-5-2-6-10-20)17-21(29)19-7-3-1-4-8-19/h1-12,15,21H,13-14,16-17H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonist activity at human LXRbeta ligand binding domain(155 to 460 residues) transfected in HEK293 cells after 16 hrs by Gal4-luciferase reporter gen...				J Med Chem 59: 3264-71 (2016) BindingDB Entry DOI: 10.7270/Q2XP76V7
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50177020 (CHEMBL3815113) Show SMILES FC(F)(F)c1ccc(CN2CCN(CC2c2ccccc2)c2ccccc2)cn1 Show InChI InChI=1S/C23H22F3N3/c24-23(25,26)22-12-11-18(15-27-22)16-29-14-13-28(20-9-5-2-6-10-20)17-21(29)19-7-3-1-4-8-19/h1-12,15,21H,13-14,16-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonist activity at human LXRalpha ligand binding domain(167 to 447 residues) transfected in HEK293 cells after 16 hrs by Gal4-luciferase reporter ge...				J Med Chem 59: 3264-71 (2016) BindingDB Entry DOI: 10.7270/Q2XP76V7
					More data for this Ligand-Target Pair