null

SMILES: CN(C)c1ccnc2sc3c(nnn(C4CCCCCC4)c3=O)c12

InChI Key: InChIKey=FHPVPCRSNMYQFP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50177096 (3-cycloheptyl -9-dimethylamino-3H-5-thia-1,2,3,6-t...) Show SMILES CN(C)c1ccnc2sc3c(nnn(C4CCCCCC4)c3=O)c12 Show InChI InChI=1S/C17H21N5OS/c1-21(2)12-9-10-18-16-13(12)14-15(24-16)17(23)22(20-19-14)11-7-5-3-4-6-8-11/h9-11H,3-8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	816	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilization				J Med Chem 48: 7374-88 (2005) Article DOI: 10.1021/jm0504407 BindingDB Entry DOI: 10.7270/Q27P8XX0
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50177096 (3-cycloheptyl -9-dimethylamino-3H-5-thia-1,2,3,6-t...) Show SMILES CN(C)c1ccnc2sc3c(nnn(C4CCCCCC4)c3=O)c12 Show InChI InChI=1S/C17H21N5OS/c1-21(2)12-9-10-18-16-13(12)14-15(24-16)17(23)22(20-19-14)11-7-5-3-4-6-8-11/h9-11H,3-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilization				J Med Chem 48: 7374-88 (2005) Article DOI: 10.1021/jm0504407 BindingDB Entry DOI: 10.7270/Q27P8XX0
					More data for this Ligand-Target Pair