null

SMILES: COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1

InChI Key: InChIKey=NFOSIFORXQYVMS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177153 (CHEMBL3814576) Show SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177153 (CHEMBL3814576) Show SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177153 (CHEMBL3814576) Show SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177153 (CHEMBL3814576) Show SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair