BDBM50177373 (S)-4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-(4-fluorophenyl)imidazolidin-2-one::CHEMBL204918
SMILES: Fc1ccc(cc1)[C@@]1(COCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)CNC(=O)N1
InChI Key: InChIKey=OEVUUUYSUGCHHG-KRWDZBQOSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Neurokinin 1 receptor (Homo sapiens (Human)) | BDBM50177373 ((S)-4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-Sar-Met Substance P from recombinant human NK1 receptor in CHO cells | Bioorg Med Chem Lett 16: 1065-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.072 BindingDB Entry DOI: 10.7270/Q2K073TJ | |||||||||||
More data for this Ligand-Target Pair |