null

SMILES: C(COc1ccc(NC2CCCCC2)cc1)CN1CCC(Cc2cnc[nH]2)CC1

InChI Key: InChIKey=RHHGOFGWHKEBMT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (GUINEA PIG)	BDBM50177527 (4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)p...) Show SMILES C(COc1ccc(NC2CCCCC2)cc1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C24H36N4O/c1-2-5-21(6-3-1)27-22-7-9-24(10-8-22)29-16-4-13-28-14-11-20(12-15-28)17-23-18-25-19-26-23/h7-10,18-21,27H,1-6,11-17H2,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50177527 (4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)p...) Show SMILES C(COc1ccc(NC2CCCCC2)cc1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C24H36N4O/c1-2-5-21(6-3-1)27-22-7-9-24(10-8-22)29-16-4-13-28-14-11-20(12-15-28)17-23-18-25-19-26-23/h7-10,18-21,27H,1-6,11-17H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CYP2D6 by human liver microsome assay				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair