BDBM50177548 3-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)propoxy)phenyl)pyridine::CHEMBL382677

SMILES: C(COc1ccc(cc1)-c1cccnc1)CN1CCC(Cc2cnc[nH]2)CC1

InChI Key: InChIKey=IKCITYWPEBNWPY-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HRH3 (GUINEA PIG)	BDBM50177548 (3-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(COc1ccc(cc1)-c1cccnc1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C23H28N4O/c1-3-21(16-24-10-1)20-4-6-23(7-5-20)28-14-2-11-27-12-8-19(9-13-27)15-22-17-25-18-26-22/h1,3-7,10,16-19H,2,8-9,11-15H2,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50177548 (3-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(COc1ccc(cc1)-c1cccnc1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C23H28N4O/c1-3-21(16-24-10-1)20-4-6-23(7-5-20)28-14-2-11-27-12-8-19(9-13-27)15-22-17-25-18-26-22/h1,3-7,10,16-19H,2,8-9,11-15H2,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CYP2D6 by human liver microsome assay				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair