BDBM50177555 1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)propoxy)phenyl)piperidine::CHEMBL379885

SMILES: C(COc1ccc(cc1)N1CCCCC1)CN1CCC(Cc2cnc[nH]2)CC1

InChI Key: InChIKey=ZNRHTIOVOPWMFW-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HRH3 (GUINEA PIG)	BDBM50177555 (1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(COc1ccc(cc1)N1CCCCC1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C23H34N4O/c1-2-12-27(13-3-1)22-5-7-23(8-6-22)28-16-4-11-26-14-9-20(10-15-26)17-21-18-24-19-25-21/h5-8,18-20H,1-4,9-17H2,(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50177555 (1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(COc1ccc(cc1)N1CCCCC1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C23H34N4O/c1-2-12-27(13-3-1)22-5-7-23(8-6-22)28-16-4-11-26-14-9-20(10-15-26)17-21-18-24-19-25-21/h5-8,18-20H,1-4,9-17H2,(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CYP2D6 by human liver microsome assay				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair