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SMILES: Nc1nc2nc(SCc3cccc(Oc4ccccc4)c3)[nH]c(=O)c2s1

InChI Key: InChIKey=WWCYRNGIGMOHBZ-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177606   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50177606
PNG
(5-(3-phenoxybenzylthio)-2-aminothiazolo[4,5-d]pyri...)
Show SMILES Nc1nc2nc(SCc3cccc(Oc4ccccc4)c3)[nH]c(=O)c2s1
Show InChI InChI=1S/C18H14N4O2S2/c19-17-20-15-14(26-17)16(23)22-18(21-15)25-10-11-5-4-8-13(9-11)24-12-6-2-1-3-7-12/h1-9H,10H2,(H3,19,20,21,22,23)
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n/an/a 480n/an/an/an/an/an/a



AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPA

Bioorg Med Chem Lett 16: 960-3 (2006)


Article DOI: 10.1016/j.bmcl.2005.10.091
BindingDB Entry DOI: 10.7270/Q2D79B09
More data for this
Ligand-Target Pair