BDBM50177611 2-(5-(2,3-difluorobenzylthio)-2-aminothiazolo[4,5-d]pyrimidin-7-ylamino)-2-methylpropan-1-ol::CHEMBL380947

SMILES: CC(C)(CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12

InChI Key: InChIKey=UTDWJMBRBOKFJV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50177611 (2-(5-(2,3-difluorobenzylthio)-2-aminothiazolo[4,5-...) Show SMILES CC(C)(CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 Show InChI InChI=1S/C16H17F2N5OS2/c1-16(2,7-24)23-13-11-12(20-14(19)26-11)21-15(22-13)25-6-8-4-3-5-9(17)10(8)18/h3-5,24H,6-7H2,1-2H3,(H3,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPA				Bioorg Med Chem Lett 16: 960-3 (2006) Article DOI: 10.1016/j.bmcl.2005.10.091 BindingDB Entry DOI: 10.7270/Q2D79B09
					More data for this Ligand-Target Pair