BDBM50177640 3-(6-methoxypyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)-1,2,4-oxadiazol-5-yl)butanoic acid::CHEMBL372749

SMILES: COc1ccc(cn1)C(CC(O)=O)Cc1nc(CCCc2ccc3CCCNc3n2)no1

InChI Key: InChIKey=YEEBBNWKQGDACU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50177640 (3-(6-methoxypyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahy...) Show SMILES COc1ccc(cn1)C(CC(O)=O)Cc1nc(CCCc2ccc3CCCNc3n2)no1 Show InChI InChI=1S/C23H27N5O4/c1-31-20-10-8-16(14-25-20)17(13-22(29)30)12-21-27-19(28-32-21)6-2-5-18-9-7-15-4-3-11-24-23(15)26-18/h7-10,14,17H,2-6,11-13H2,1H3,(H,24,26)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Integrin alpha2bbeta3 receptor by SPRA assay				Bioorg Med Chem Lett 16: 839-44 (2006) Article DOI: 10.1016/j.bmcl.2005.11.008 BindingDB Entry DOI: 10.7270/Q28K78NF
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50177640 (3-(6-methoxypyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahy...) Show SMILES COc1ccc(cn1)C(CC(O)=O)Cc1nc(CCCc2ccc3CCCNc3n2)no1 Show InChI InChI=1S/C23H27N5O4/c1-31-20-10-8-16(14-25-20)17(13-22(29)30)12-21-27-19(28-32-21)6-2-5-18-9-7-15-4-3-11-24-23(15)26-18/h7-10,14,17H,2-6,11-13H2,1H3,(H,24,26)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Integrin alphav-beta3 receptor by SPRA assay				Bioorg Med Chem Lett 16: 839-44 (2006) Article DOI: 10.1016/j.bmcl.2005.11.008 BindingDB Entry DOI: 10.7270/Q28K78NF
					More data for this Ligand-Target Pair