BDBM50177711 (5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepten-7-yl)-acetic acid::CHEMBL202156
SMILES: OC(=O)Cc1ccc2SCc3ccccc3C(=O)c2c1
InChI Key: InChIKey=URRFMRCFYIOQKV-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Helicase IV (Escherichia coli (strain K12)) | BDBM50177711 ((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA) | Bioorg Med Chem Lett 16: 923-7 (2006) Article DOI: 10.1016/j.bmcl.2005.10.110 BindingDB Entry DOI: 10.7270/Q2MS3SB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Helicase IV (Escherichia coli (strain K12)) | BDBM50177711 ((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of ATPase activity of Tyr473Ala mutated Helicase4 in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA) | Bioorg Med Chem Lett 16: 923-7 (2006) Article DOI: 10.1016/j.bmcl.2005.10.110 BindingDB Entry DOI: 10.7270/Q2MS3SB8 | |||||||||||
More data for this Ligand-Target Pair |