BDBM50177898 2-Fluoro-N-[4-methoxymethyl-1-(2-thiophen-2-yl-ethyl)-piperidin-4-yl]-N-phenyl-propionamide::CHEMBL196960::N-[1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenyl-2-[(+/-)-[18F]fluoropropanamide

SMILES: COCC1(CCN(CCc2cccs2)CC1)N(C(=O)C(C)F)c1ccccc1

InChI Key: InChIKey=JSQPDFXSOMVVSP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (MOUSE)	BDBM50177898 (2-Fluoro-N-[4-methoxymethyl-1-(2-thiophen-2-yl-eth...) Show SMILES COCC1(CCN(CCc2cccs2)CC1)N(C(=O)C(C)F)c1ccccc1 Show InChI InChI=1S/C22H29FN2O2S/c1-18(23)21(26)25(19-7-4-3-5-8-19)22(17-27-2)11-14-24(15-12-22)13-10-20-9-6-16-28-20/h3-9,16,18H,10-15,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t M£nchen Curated by ChEMBL					Assay Description Binding constant for Opioid receptor mu 1 in mouse				Bioorg Med Chem Lett 15: 1773-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.049 BindingDB Entry DOI: 10.7270/Q28916M4
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50177898 (2-Fluoro-N-[4-methoxymethyl-1-(2-thiophen-2-yl-eth...) Show SMILES COCC1(CCN(CCc2cccs2)CC1)N(C(=O)C(C)F)c1ccccc1 Show InChI InChI=1S/C22H29FN2O2S/c1-18(23)21(26)25(19-7-4-3-5-8-19)22(17-27-2)11-14-24(15-12-22)13-10-20-9-6-16-28-20/h3-9,16,18H,10-15,17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universität München Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from recombinant human mu opioid receptor				J Med Chem 48: 7720-32 (2005) Article DOI: 10.1021/jm0507274 BindingDB Entry DOI: 10.7270/Q2G44PVB
					More data for this Ligand-Target Pair