BDBM50177943 2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyphenyl)acryloylamino]propyl}-3-(3,4-dihydroxy-5-methoxyphenyl)acrylamide::CHEMBL197374

SMILES: COc1cc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O

InChI Key: InChIKey=QXXKYNSVEFAGIU-KGMKFKQSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-1 (Homo sapiens (Human))	BDBM50177943 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...) Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C25H24N4O8/c1-36-20-10-14(8-18(30)22(20)32)6-16(12-26)24(34)28-4-3-5-29-25(35)17(13-27)7-15-9-19(31)23(33)21(11-15)37-2/h6-11,30-33H,3-5H2,1-2H3,(H,28,34)(H,29,35)/b16-6+,17-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair