BDBM50177955 2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyphenyl)acryloylamino]ethyl}-3-(3,4-dihydroxy-5-methoxyphenyl)acrylamide::CHEMBL198915

SMILES: COc1cc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O

InChI Key: InChIKey=GHHPOUGOEFAMFV-IAGONARPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-1 (Homo sapiens (Human))	BDBM50177955 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...) Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C24H22N4O8/c1-35-19-9-13(7-17(29)21(19)31)5-15(11-25)23(33)27-3-4-28-24(34)16(12-26)6-14-8-18(30)22(32)20(10-14)36-2/h5-10,29-32H,3-4H2,1-2H3,(H,27,33)(H,28,34)/b15-5+,16-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair