Found 4 hits for monomerid = 50178491 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178491
(5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydr...)Show SMILES COC(=O)c1c(OCCCN(C)C)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12 Show InChI InChI=1S/C27H23NO6/c1-28(2)13-8-14-33-24-17-11-6-7-12-18(17)25-19(21(24)27(31)32-3)20-22(29)15-9-4-5-10-16(15)23(30)26(20)34-25/h4-7,9-12H,8,13-14H2,1-3H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibitory activity against FGFR1 kinase |
Bioorg Med Chem Lett 16: 737-42 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50178491
(5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydr...)Show SMILES COC(=O)c1c(OCCCN(C)C)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12 Show InChI InChI=1S/C27H23NO6/c1-28(2)13-8-14-33-24-17-11-6-7-12-18(17)25-19(21(24)27(31)32-3)20-22(29)15-9-4-5-10-16(15)23(30)26(20)34-25/h4-7,9-12H,8,13-14H2,1-3H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibitory activity against EGFR kinase |
Bioorg Med Chem Lett 16: 737-42 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178491
(5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydr...)Show SMILES COC(=O)c1c(OCCCN(C)C)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12 Show InChI InChI=1S/C27H23NO6/c1-28(2)13-8-14-33-24-17-11-6-7-12-18(17)25-19(21(24)27(31)32-3)20-22(29)15-9-4-5-10-16(15)23(30)26(20)34-25/h4-7,9-12H,8,13-14H2,1-3H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibitory activity against VEGFR2 kinase |
Bioorg Med Chem Lett 16: 737-42 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50178491
(5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydr...)Show SMILES COC(=O)c1c(OCCCN(C)C)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12 Show InChI InChI=1S/C27H23NO6/c1-28(2)13-8-14-33-24-17-11-6-7-12-18(17)25-19(21(24)27(31)32-3)20-22(29)15-9-4-5-10-16(15)23(30)26(20)34-25/h4-7,9-12H,8,13-14H2,1-3H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibitory activity against PDGFRbeta kinase |
Bioorg Med Chem Lett 16: 737-42 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR |
More data for this
Ligand-Target Pair | |
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