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SMILES: COC(=O)c1c(OC)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12

InChI Key: InChIKey=UOWBWTAGELTSTG-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178493   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50178493
PNG
(5-methoxy-7,12-dioxo-7,12-dihydro-dinaphtho[1,2-b;...)
Show SMILES COC(=O)c1c(OC)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12
Show InChI InChI=1S/C23H14O6/c1-27-20-13-9-5-6-10-14(13)21-15(17(20)23(26)28-2)16-18(24)11-7-3-4-8-12(11)19(25)22(16)29-21/h3-10H,1-2H3
PDB
MMDB

KEGG

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against EGFR kinase


Bioorg Med Chem Lett 16: 737-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50178493
PNG
(5-methoxy-7,12-dioxo-7,12-dihydro-dinaphtho[1,2-b;...)
Show SMILES COC(=O)c1c(OC)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12
Show InChI InChI=1S/C23H14O6/c1-27-20-13-9-5-6-10-14(13)21-15(17(20)23(26)28-2)16-18(24)11-7-3-4-8-12(11)19(25)22(16)29-21/h3-10H,1-2H3
PDB
MMDB

NCI pathway
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KEGG

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against PDGFRbeta kinase


Bioorg Med Chem Lett 16: 737-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50178493
PNG
(5-methoxy-7,12-dioxo-7,12-dihydro-dinaphtho[1,2-b;...)
Show SMILES COC(=O)c1c(OC)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12
Show InChI InChI=1S/C23H14O6/c1-27-20-13-9-5-6-10-14(13)21-15(17(20)23(26)28-2)16-18(24)11-7-3-4-8-12(11)19(25)22(16)29-21/h3-10H,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against FGFR1 kinase


Bioorg Med Chem Lett 16: 737-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR
More data for this
Ligand-Target Pair