Found 4 hits for monomerid = 50178494 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50178494
(5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-...)Show SMILES CCN(CC)CCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O Show InChI InChI=1S/C28H25NO6/c1-4-29(5-2)14-15-34-25-18-12-8-9-13-19(18)26-20(22(25)28(32)33-3)21-23(30)16-10-6-7-11-17(16)24(31)27(21)35-26/h6-13H,4-5,14-15H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against PDGFRbeta kinase |
Bioorg Med Chem Lett 16: 737-42 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.115 BindingDB Entry DOI: 10.7270/Q2SF2VQR |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178494
(5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-...)Show SMILES CCN(CC)CCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O Show InChI InChI=1S/C28H25NO6/c1-4-29(5-2)14-15-34-25-18-12-8-9-13-19(18)26-20(22(25)28(32)33-3)21-23(30)16-10-6-7-11-17(16)24(31)27(21)35-26/h6-13H,4-5,14-15H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against VEGFR2 kinase |
Bioorg Med Chem Lett 16: 737-42 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.115 BindingDB Entry DOI: 10.7270/Q2SF2VQR |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50178494
(5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-...)Show SMILES CCN(CC)CCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O Show InChI InChI=1S/C28H25NO6/c1-4-29(5-2)14-15-34-25-18-12-8-9-13-19(18)26-20(22(25)28(32)33-3)21-23(30)16-10-6-7-11-17(16)24(31)27(21)35-26/h6-13H,4-5,14-15H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against EGFR kinase |
Bioorg Med Chem Lett 16: 737-42 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.115 BindingDB Entry DOI: 10.7270/Q2SF2VQR |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178494
(5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-...)Show SMILES CCN(CC)CCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O Show InChI InChI=1S/C28H25NO6/c1-4-29(5-2)14-15-34-25-18-12-8-9-13-19(18)26-20(22(25)28(32)33-3)21-23(30)16-10-6-7-11-17(16)24(31)27(21)35-26/h6-13H,4-5,14-15H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against FGFR1 kinase |
Bioorg Med Chem Lett 16: 737-42 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.115 BindingDB Entry DOI: 10.7270/Q2SF2VQR |
More data for this Ligand-Target Pair | |