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SMILES: CC(C)(C(=O)Nc1ccccc1-c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=DIMLTFVHIUSASS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178549   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))		BDBM50178549
PNG
(CHEMBL206016 | N-biphenyl-2-yl-2-(3,5-bis-trifluor...)
Show SMILES CC(C)(C(=O)Nc1ccccc1-c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C24H19F6NO/c1-22(2,16-12-17(23(25,26)27)14-18(13-16)24(28,29)30)21(32)31-20-11-7-6-10-19(20)15-8-4-3-5-9-15/h3-14H,1-2H3,(H,31,32)
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MMDB

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Article
PubMed
 1.38E+3n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-labeled substance P from cloned human NK1 receptor expressed in CHO cells

Bioorg Med Chem Lett 16: 1362-5 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.047
BindingDB Entry DOI: 10.7270/Q2D50MJP
More data for this
Ligand-Target Pair