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SMILES: CN(C(=O)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1-c1ccccc1

InChI Key: InChIKey=YPDPPCHRJSBOBT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178556   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))		BDBM50178556
PNG
(CHEMBL381744 | N-biphenyl-2-yl-2-(3,5-bis-trifluor...)
Show SMILES CN(C(=O)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1-c1ccccc1
Show InChI InChI=1S/C23H17F6NO/c1-30(20-10-6-5-9-19(20)16-7-3-2-4-8-16)21(31)13-15-11-17(22(24,25)26)14-18(12-15)23(27,28)29/h2-12,14H,13H2,1H3
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Article
PubMed
 562n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-labeled substance P from cloned human NK1 receptor expressed in CHO cells

Bioorg Med Chem Lett 16: 1362-5 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.047
BindingDB Entry DOI: 10.7270/Q2D50MJP
More data for this
Ligand-Target Pair