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SMILES: CN(C(=O)c1ccccc1-c1ccccc1)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=MOSUQXLFKFQKGI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178559   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))		BDBM50178559
PNG
(CHEMBL436951 | biphenyl-2-carboxylic acid [1-(3,5-...)
Show SMILES CN(C(=O)c1ccccc1-c1ccccc1)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C25H21F6NO/c1-23(2,17-13-18(24(26,27)28)15-19(14-17)25(29,30)31)32(3)22(33)21-12-8-7-11-20(21)16-9-5-4-6-10-16/h4-15H,1-3H3
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MMDB

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Similars
Article
PubMed
 295n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-labeled substance P from cloned human NK1 receptor expressed in CHO cells

Bioorg Med Chem Lett 16: 1362-5 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.047
BindingDB Entry DOI: 10.7270/Q2D50MJP
More data for this
Ligand-Target Pair