null

SMILES: CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(=O)NCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@H](Cc2c(C)cc(O)cc2C)N(C)C)nc1C

InChI Key: InChIKey=GDJAYRWKBABTAT-VRNAFJHGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50178754 (3,6-bis-(N,N-dimethyl-Dmt-Tic-NH-propyl)-2(1H)-pyr...) Show SMILES CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(=O)NCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@H](Cc2c(C)cc(O)cc2C)N(C)C)nc1C Show InChI InChI=1S/C57H72N8O7/c1-34-24-43(66)25-35(2)45(34)30-51(62(6)7)56(71)64-32-41-18-12-10-16-39(41)28-49(64)54(69)58-22-14-20-47-38(5)60-48(53(68)61-47)21-15-23-59-55(70)50-29-40-17-11-13-19-42(40)33-65(50)57(72)52(63(8)9)31-46-36(3)26-44(67)27-37(46)4/h10-13,16-19,24-27,49-52,66-67H,14-15,20-23,28-33H2,1-9H3,(H,58,69)(H,59,70)(H,61,68)/t49?,50?,51-,52-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.287	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]deltorphin-II from delta opioid receptor in rat brain synaptosomal membranes				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50178754 (3,6-bis-(N,N-dimethyl-Dmt-Tic-NH-propyl)-2(1H)-pyr...) Show SMILES CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(=O)NCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@H](Cc2c(C)cc(O)cc2C)N(C)C)nc1C Show InChI InChI=1S/C57H72N8O7/c1-34-24-43(66)25-35(2)45(34)30-51(62(6)7)56(71)64-32-41-18-12-10-16-39(41)28-49(64)54(69)58-22-14-20-47-38(5)60-48(53(68)61-47)21-15-23-59-55(70)50-29-40-17-11-13-19-42(40)33-65(50)57(72)52(63(8)9)31-46-36(3)26-44(67)27-37(46)4/h10-13,16-19,24-27,49-52,66-67H,14-15,20-23,28-33H2,1-9H3,(H,58,69)(H,59,70)(H,61,68)/t49?,50?,51-,52-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in rat brain synaptosomal membranes				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50178754 (3,6-bis-(N,N-dimethyl-Dmt-Tic-NH-propyl)-2(1H)-pyr...) Show SMILES CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(=O)NCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@H](Cc2c(C)cc(O)cc2C)N(C)C)nc1C Show InChI InChI=1S/C57H72N8O7/c1-34-24-43(66)25-35(2)45(34)30-51(62(6)7)56(71)64-32-41-18-12-10-16-39(41)28-49(64)54(69)58-22-14-20-47-38(5)60-48(53(68)61-47)21-15-23-59-55(70)50-29-40-17-11-13-19-42(40)33-65(50)57(72)52(63(8)9)31-46-36(3)26-44(67)27-37(46)4/h10-13,16-19,24-27,49-52,66-67H,14-15,20-23,28-33H2,1-9H3,(H,58,69)(H,59,70)(H,61,68)/t49?,50?,51-,52-/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Agonistic activity at mu opioid receptor in myenteric plexus longitudinal muscle of guinea pig ileum				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50178754 (3,6-bis-(N,N-dimethyl-Dmt-Tic-NH-propyl)-2(1H)-pyr...) Show SMILES CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(=O)NCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@H](Cc2c(C)cc(O)cc2C)N(C)C)nc1C Show InChI InChI=1S/C57H72N8O7/c1-34-24-43(66)25-35(2)45(34)30-51(62(6)7)56(71)64-32-41-18-12-10-16-39(41)28-49(64)54(69)58-22-14-20-47-38(5)60-48(53(68)61-47)21-15-23-59-55(70)50-29-40-17-11-13-19-42(40)33-65(50)57(72)52(63(8)9)31-46-36(3)26-44(67)27-37(46)4/h10-13,16-19,24-27,49-52,66-67H,14-15,20-23,28-33H2,1-9H3,(H,58,69)(H,59,70)(H,61,68)/t49?,50?,51-,52-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Agonistic activity at delta opioid receptor in mouse vas deferens				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
					More data for this Ligand-Target Pair