null

SMILES: Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1[nH]c(=O)c(CNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C

InChI Key: InChIKey=BOYVBTQTUISOKQ-XQIDWOBFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50178755 (3,6-bis(Dmt-Tic-NH-methyl)-2(1H)-pyrazinone | CHEM...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1[nH]c(=O)c(CNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C49H56N8O7/c1-26-14-35(58)15-27(2)37(26)20-39(50)48(63)56-24-33-12-8-6-10-31(33)18-43(56)46(61)52-22-41-30(5)54-42(45(60)55-41)23-53-47(62)44-19-32-11-7-9-13-34(32)25-57(44)49(64)40(51)21-38-28(3)16-36(59)17-29(38)4/h6-17,39-40,43-44,58-59H,18-25,50-51H2,1-5H3,(H,52,61)(H,53,62)(H,55,60)/t39-,40-,43?,44?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.163	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]deltorphin-II from delta opioid receptor in rat brain synaptosomal membranes				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50178755 (3,6-bis(Dmt-Tic-NH-methyl)-2(1H)-pyrazinone | CHEM...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1[nH]c(=O)c(CNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C49H56N8O7/c1-26-14-35(58)15-27(2)37(26)20-39(50)48(63)56-24-33-12-8-6-10-31(33)18-43(56)46(61)52-22-41-30(5)54-42(45(60)55-41)23-53-47(62)44-19-32-11-7-9-13-34(32)25-57(44)49(64)40(51)21-38-28(3)16-36(59)17-29(38)4/h6-17,39-40,43-44,58-59H,18-25,50-51H2,1-5H3,(H,52,61)(H,53,62)(H,55,60)/t39-,40-,43?,44?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in rat brain synaptosomal membranes				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50178755 (3,6-bis(Dmt-Tic-NH-methyl)-2(1H)-pyrazinone | CHEM...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1[nH]c(=O)c(CNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C49H56N8O7/c1-26-14-35(58)15-27(2)37(26)20-39(50)48(63)56-24-33-12-8-6-10-31(33)18-43(56)46(61)52-22-41-30(5)54-42(45(60)55-41)23-53-47(62)44-19-32-11-7-9-13-34(32)25-57(44)49(64)40(51)21-38-28(3)16-36(59)17-29(38)4/h6-17,39-40,43-44,58-59H,18-25,50-51H2,1-5H3,(H,52,61)(H,53,62)(H,55,60)/t39-,40-,43?,44?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Agonistic activity at delta opioid receptor in mouse vas deferens				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50178755 (3,6-bis(Dmt-Tic-NH-methyl)-2(1H)-pyrazinone | CHEM...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1[nH]c(=O)c(CNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C49H56N8O7/c1-26-14-35(58)15-27(2)37(26)20-39(50)48(63)56-24-33-12-8-6-10-31(33)18-43(56)46(61)52-22-41-30(5)54-42(45(60)55-41)23-53-47(62)44-19-32-11-7-9-13-34(32)25-57(44)49(64)40(51)21-38-28(3)16-36(59)17-29(38)4/h6-17,39-40,43-44,58-59H,18-25,50-51H2,1-5H3,(H,52,61)(H,53,62)(H,55,60)/t39-,40-,43?,44?/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Agonistic activity at mu opioid receptor in myenteric plexus longitudinal muscle of guinea pig ileum				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
					More data for this Ligand-Target Pair