null

SMILES: NC(=O)C1CCc2c(C1)[nH]c1ccc(Cl)cc21

InChI Key: InChIKey=AAALFTUMOWSRRM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta sliding clamp (Escherichia coli (strain K12))	BDBM50178789 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxa...) Show SMILES NC(=O)C1CCc2c(C1)[nH]c1ccc(Cl)cc21 Show InChI InChI=1S/C13H13ClN2O/c14-8-2-4-11-10(6-8)9-3-1-7(13(15)17)5-12(9)16-11/h2,4,6-7,16H,1,3,5H2,(H2,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong and The Illawarra Health and Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay				J Med Chem 58: 4693-702 (2015) Article DOI: 10.1021/acs.jmedchem.5b00232 BindingDB Entry DOI: 10.7270/Q2KK9DJ9
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50178789 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxa...) Show SMILES NC(=O)C1CCc2c(C1)[nH]c1ccc(Cl)cc21 Show InChI InChI=1S/C13H13ClN2O/c14-8-2-4-11-10(6-8)9-3-1-7(13(15)17)5-12(9)16-11/h2,4,6-7,16H,1,3,5H2,(H2,15,17)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Elixir Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assay				J Med Chem 48: 8045-54 (2005) Article DOI: 10.1021/jm050522v BindingDB Entry DOI: 10.7270/Q27D2TPK
					More data for this Ligand-Target Pair