BDBM50178811 CHEMBL199020::N-(3-aminopropyl)-4-tert-butyl-N,N-dimethylbenzenaminium
SMILES: CC(C)(C)c1ccc(cc1)[N+](C)(C)CCCN
InChI Key: InChIKey=YVVNAYUSFCYGPS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trypanothione reductase (Trypanosoma cruzi) | BDBM50178811 (CHEMBL199020 | N-(3-aminopropyl)-4-tert-butyl-N,N-...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester Curated by ChEMBL | Assay Description Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrate | J Med Chem 48: 8087-97 (2005) Article DOI: 10.1021/jm050819t BindingDB Entry DOI: 10.7270/Q2V69J65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM50178811 (CHEMBL199020 | N-(3-aminopropyl)-4-tert-butyl-N,N-...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester Curated by ChEMBL | Assay Description Inhibitory activity aganist trypanothione reductase from Trypanosoma cruzi using 0.12 mM TSST substrate | J Med Chem 48: 8087-97 (2005) Article DOI: 10.1021/jm050819t BindingDB Entry DOI: 10.7270/Q2V69J65 | |||||||||||
More data for this Ligand-Target Pair |