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SMILES: OC(CCc1cccc(OC(F)(F)F)c1)[C@@H]1CCC[C@H]1C(=O)NCc1ccccc1

InChI Key: InChIKey=MUMKGUWBPCCLCG-OSBQEZSISA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178865   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM50178865
PNG
(CHEMBL203440 | trans-N-benzyl-2-(1-hydroxy-3-(3-(t...)
Show SMILES OC(CCc1cccc(OC(F)(F)F)c1)[C@@H]1CCC[C@H]1C(=O)NCc1ccccc1
Show InChI InChI=1S/C23H26F3NO3/c24-23(25,26)30-18-9-4-8-16(14-18)12-13-21(28)19-10-5-11-20(19)22(29)27-15-17-6-2-1-3-7-17/h1-4,6-9,14,19-21,28H,5,10-13,15H2,(H,27,29)/t19-,20-,21?/m1/s1
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KEGG

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Similars
Article
PubMed
 230n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7

Bioorg Med Chem Lett 16: 1358-61 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S
More data for this
Ligand-Target Pair