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SMILES: Fc1cc2c(cc1-c1cccnc1F)n(C1CC1)c1s[nH]c(=O)c1c2=O

InChI Key: InChIKey=BGWYQEFQCMRJGY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178905   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 4 subunit A


(Staphylococcus aureus)		BDBM50178905
PNG
(9-cyclopropyl-6-fluoro-7-(2-fluoropyridin-3-yl)iso...)
Show SMILES Fc1cc2c(cc1-c1cccnc1F)n(C1CC1)c1s[nH]c(=O)c1c2=O
Show InChI InChI=1S/C18H11F2N3O2S/c19-12-6-11-13(7-10(12)9-2-1-5-21-16(9)20)23(8-3-4-8)18-14(15(11)24)17(25)22-26-18/h1-2,5-8H,3-4H2,(H,22,25)
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Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Staphylococcus aureus ATCC 29213 wild type Topo 4

Bioorg Med Chem Lett 16: 1277-81 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.064
BindingDB Entry DOI: 10.7270/Q26D5SKN
More data for this
Ligand-Target Pair